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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFF4AF4/FMR2 family member 4. (1161 aa)    
Predicted Functional Partners:
CCNT1
Cyclin-T1; Belongs to the cyclin family.
   
 0.990
CDK9
Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily.
    
 0.988
ELL
RNA polymerase II elongation factor ELL.
   
 0.965
CCNT2
Cyclin-T2; Belongs to the cyclin family.
   
 0.951
EAF2
ELL-associated factor 2.
    
 0.921
MLLT1
Protein ENL.
    
 0.897
MLLT3
Protein AF-9.
    
 0.897
LOC110480675
ELL-associated factor 1.
    
 0.881
ENSLSDP00000025762
annotation not available
    
 0.822
AFF1
AF4/FMR2 family member 1.
    
0.804
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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