Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPRY4Protein sprouty 4. (297 aa)    
Predicted Functional Partners:
TESK1
Dual specificity testis-specific protein kinase 1.
    
 0.812
TESK2
Dual specificity testis-specific protein kinase 2.
    
 0.698
IL17RD
Interleukin-17 receptor D.
   
  
 0.685
CBL
E3 ubiquitin-protein ligase CBL.
    
 0.681
CBLB
E3 ubiquitin-protein ligase CBL-B.
    
 0.681
FGF8
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
   
  
 0.588
GRB2
Growth factor receptor-bound protein 2.
    
 0.567
DUSP6
Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
   
  
 0.553
TRIP4
Activating signal cointegrator 1.
      
 0.526
PTPN11
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
    
 0.524
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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