Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BUB1BMitotic checkpoint serine/threonine-protein kinase BUB1 beta. (281 aa)    
Predicted Functional Partners:
BUB3
Mitotic checkpoint protein BUB3.
   
 0.999
CDC20
Cell division cycle protein 20.
   
 0.999
MAD2L1
Mitotic spindle assembly checkpoint protein MAD2A.
   
 0.999
PLK1
Serine/threonine-protein kinase PLK.
   
 0.998
ENSLSDP00000019602
annotation not available
   
 0.998
NDC80
Kinetochore protein NDC80.
   
 0.996
NEK2
Serine/threonine-protein kinase Nek2.
   
 0.996
CDK1
Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.993
CDC23
Cell division cycle protein 23.
   
 0.993
CDC27
Cell division cycle protein 27.
    
 0.992
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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