STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAF1RNA polymerase II-associated factor 1. (531 aa)    
Predicted Functional Partners:
CDC73
Parafibromin.
   
 0.999
LEO1
RNA polymerase-associated protein LEO1.
   
 0.999
CTR9
RNA polymerase-associated protein CTR9.
   
 0.998
RTF1
RNA polymerase-associated protein RTF1.
   
 0.996
CINP
Cyclin-dependent kinase 2-interacting protein.
   
 0.972
SSRP1
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
   
 0.959
SUPT16H
FACT complex subunit SPT16.
    
 0.959
LOC110479828
WD repeat-containing protein 61.
   
 0.945
WDR61
WD repeat-containing protein 61.
   
 0.945
POLR2C
DNA-directed RNA polymerase II subunit RPB3.
   
 0.939
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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