Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SH3GL2Endophilin-A1. (373 aa)    
Predicted Functional Partners:
CBL
E3 ubiquitin-protein ligase CBL.
    
  0.876
CBLB
E3 ubiquitin-protein ligase CBL-B.
    
  0.876
SYNJ1
Synaptojanin-1.
    
 
 0.837
GAK
Cyclin-G-associated kinase.
   
 
 0.805
EGFR
Receptor protein-tyrosine kinase.
    
 0.797
SYNJ2
Synaptojanin-2.
    
 
 0.722
IGF1R
Tyrosine-protein kinase receptor.
    
  0.674
FGFR3
Fibroblast growth factor receptor.
   
 
  0.657
DNAJC6
Putative tyrosine-protein phosphatase auxilin.
   
 
 0.653
DNM1
Dynamin-1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
   
 0.652
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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