FOCAD protein (Lonchura striata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

FOCAD

Focadhesin. (1794 aa)

Predicted Functional Partners:

PTPLAD2

0.584

ENSLSDP00000003776

0.526

TTC37

0.476

EXOSC5

0.446

Your Current Organism:

Lonchura striata

NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLSDP00000003776	EXOSC5	ENSLSDP00000003776	ENSLSDP00000012714	annotation not available	Exosome complex component RRP46.	0.934
ENSLSDP00000003776	FOCAD	ENSLSDP00000003776	ENSLSDP00000005980	annotation not available	Focadhesin.	0.526
ENSLSDP00000003776	TTC37	ENSLSDP00000003776	ENSLSDP00000024341	annotation not available	Tetratricopeptide repeat protein 37.	0.998
EXOSC5	ENSLSDP00000003776	ENSLSDP00000012714	ENSLSDP00000003776	Exosome complex component RRP46.	annotation not available	0.934
EXOSC5	FOCAD	ENSLSDP00000012714	ENSLSDP00000005980	Exosome complex component RRP46.	Focadhesin.	0.446
EXOSC5	TTC37	ENSLSDP00000012714	ENSLSDP00000024341	Exosome complex component RRP46.	Tetratricopeptide repeat protein 37.	0.881
FOCAD	ENSLSDP00000003776	ENSLSDP00000005980	ENSLSDP00000003776	Focadhesin.	annotation not available	0.526
FOCAD	EXOSC5	ENSLSDP00000005980	ENSLSDP00000012714	Focadhesin.	Exosome complex component RRP46.	0.446
FOCAD	PTPLAD2	ENSLSDP00000005980	ENSLSDP00000012723	Focadhesin.	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	0.584
FOCAD	TTC37	ENSLSDP00000005980	ENSLSDP00000024341	Focadhesin.	Tetratricopeptide repeat protein 37.	0.476
PTPLAD2	FOCAD	ENSLSDP00000012723	ENSLSDP00000005980	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Focadhesin.	0.584
TTC37	ENSLSDP00000003776	ENSLSDP00000024341	ENSLSDP00000003776	Tetratricopeptide repeat protein 37.	annotation not available	0.998
TTC37	EXOSC5	ENSLSDP00000024341	ENSLSDP00000012714	Tetratricopeptide repeat protein 37.	Exosome complex component RRP46.	0.881
TTC37	FOCAD	ENSLSDP00000024341	ENSLSDP00000005980	Tetratricopeptide repeat protein 37.	Focadhesin.	0.476