Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PDE10APhosphodiesterase. (1061 aa)    
Predicted Functional Partners:
ENPP1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1.
     
 0.928
ENPP3
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3.
     
 0.928
ADK
Adenosine kinase.
     
 0.924
AK3
GTP:AMP phosphotransferase AK3, mitochondrial; Belongs to the adenylate kinase family.
     
 0.924
RPS12
40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family.
    
   0.917
GMPR
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
    
 0.912
APRT
Adenine phosphoribosyltransferase.
     
 0.907
GUK1
Guanylate kinase.
   
 
 0.903
GMPS
GMP synthase [glutamine-hydrolyzing].
     
  0.900
ADSL
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
     
 0.900
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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