Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AXIN1Axin-1. (842 aa)    
Predicted Functional Partners:
GSK3B
Glycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily.
   
 0.996
CTNNB1
Catenin beta-1.
    
 0.996
APC
Adenomatous polyposis coli protein.
   
 0.994
CSNK1A1
Casein kinase I isoform alpha; Belongs to the protein kinase superfamily.
    
 0.994
DVL3
Segment polarity protein dishevelled DVL-3.
   
0.984
DVL1
Segment polarity protein dishevelled DVL-1.
   
 0.984
CSNK1E
Casein kinase I isoform epsilon; Belongs to the protein kinase superfamily.
    
 0.964
TNKS
Poly [ADP-ribose] polymerase.
    
 0.936
LRP6
Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.
    
 0.923
AMER1
APC membrane recruitment protein 1.
    
 0.914
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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