Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADIGAdipogenin. (66 aa)    
Predicted Functional Partners:
RALGAPB
Ral GTPase-activating protein subunit beta.
      
 0.710
PPP1R16B
Protein phosphatase 1 regulatory inhibitor subunit 16B.
      
 0.624
LPL
Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
      
 0.569
MRPL17
39S ribosomal protein L17, mitochondrial; Belongs to the bacterial ribosomal protein bL17 family.
      
 0.567
PDE8B
Phosphodiesterase.
      
 0.527
PDE8A
Phosphodiesterase.
      
 0.527
NR0B2
Nuclear receptor subfamily 0 group B member 2.
      
 0.456
HSPB7
Heat shock protein beta-7; Belongs to the small heat shock protein (HSP20) family.
      
 0.445
COCH
Cochlin.
      
 0.426
MDFIC2
Uncharacterized protein.
      
 0.411
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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