STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIAS2E3 SUMO-protein ligase PIAS2. (621 aa)    
Predicted Functional Partners:
SUMO1
Small ubiquitin-related modifier 1.
    
 0.980
PIAS4
E3 SUMO-protein ligase PIAS4.
  
 
0.932
PIAS1
E3 SUMO-protein ligase PIAS1.
  
 
 
0.919
UBE2I
SUMO-conjugating enzyme UBC9; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.913
KCTD2
BTB/POZ domain-containing protein KCTD2.
    
 0.814
ENSLSDP00000000815
Small ubiquitin-related modifier 3-like.
    
 0.798
SUMO2
Small ubiquitin-related modifier.
    
 0.798
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 
 0.704
UBE2N
Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.696
SHOC2
Leucine-rich repeat protein SHOC-2.
   
  
 0.673
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.