Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
RHBDF1Inactive rhomboid protein 1. (857 aa)    
Predicted Functional Partners:
ADAM17
Disintegrin and metalloproteinase domain-containing protein 17.
    
 0.851
ADAM10
Disintegrin and metalloproteinase domain-containing protein 10.
    
 0.599
ETFA
Electron transfer flavoprotein subunit alpha, mitochondrial.
     
 0.590
PHLDB1
Pleckstrin homology like domain family B member 1.
   
  
 0.580
METTL23
Methyltransferase-like protein 23.
    
 
 0.570
PRPSAP1
Phosphoribosyl pyrophosphate synthase-associated protein 1.
      
 0.568
NPRL3
Nitrogen permease regulator 3-like protein.
      
 0.567
LCMT1
Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family.
      
 0.565
LMF1
Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family.
      
 0.565
MEGF11
Multiple epidermal growth factor-like domains protein 11.
   
  
 0.564
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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