STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAD9BCell cycle checkpoint control protein; Belongs to the rad9 family. (424 aa)    
Predicted Functional Partners:
RAD1
Cell cycle checkpoint protein RAD1.
    
 0.998
HUS1
Checkpoint protein; Belongs to the HUS1 family.
    
 0.994
RAD17
Cell cycle checkpoint protein RAD17.
   
 0.993
RFC4
Replication factor C subunit 4.
   
 0.983
TOPBP1
DNA topoisomerase 2-binding protein 1.
    
 0.981
RFC2
Replication factor C subunit 2.
   
 0.979
WRN
Werner syndrome ATP-dependent helicase.
   
 0.977
RFC3
Replication factor C subunit 3.
   
 0.976
RFC5
Replication factor C subunit 5.
   
 0.965
RPA1
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
   
 0.947
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.