Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PMEPA1Protein TMEPAI. (302 aa)    
Predicted Functional Partners:
SMAD3
Mothers against decapentaplegic homolog.
    
 0.868
SMAD2
Mothers against decapentaplegic homolog.
    
 0.868
RPS2
40S ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.
   
 0.833
WWP2
E3 ubiquitin-protein ligase.
    
 
 0.730
SMURF1
E3 ubiquitin-protein ligase.
    
   0.729
NEDD4
E3 ubiquitin-protein ligase.
    
 
 0.653
SETD1B
Histone-lysine N-methyltransferase SETD1B.
    
 0.646
NEDD4L
E3 ubiquitin-protein ligase NEDD4-like.
    
 
 0.646
GAR1
H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
   
 
 0.644
NHP2
Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.
   
 0.632
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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