Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPO11Meiotic recombination protein SPO11. (358 aa)    
Predicted Functional Partners:
DMC1
DNA meiotic recombinase 1.
   
 0.952
RAD50
DNA repair protein RAD50.
    
 0.918
ADK
Adenosine kinase.
      
 0.874
SYCP3
Synaptonemal complex protein 3.
      
 0.874
SYCE2
Synaptonemal complex central element protein 2.
      
 0.873
MRE11
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
 0.872
LOC110479828
WD repeat-containing protein 61.
    
 
 0.827
WDR61
WD repeat-containing protein 61.
    
 
 0.827
ENSLSDP00000020172
annotation not available
   
 
 0.814
XRCC3
DNA repair protein XRCC3.
    
 0.810
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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