Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TNKSPoly [ADP-ribose] polymerase. (1266 aa)    
Predicted Functional Partners:
RNF146
E3 ubiquitin-protein ligase RNF146.
    
 0.984
GMDS
GDP-mannose 4,6 dehydratase.
    
 
 0.975
TNKS2
Poly [ADP-ribose] polymerase.
   
  0.967
AXIN1
Axin-1.
    
 0.936
AXIN2
Axin-2.
    
 0.927
BABAM1
BRISC and BRCA1-A complex member 1.
    
 0.924
TNKS1BP1
Tankyrase-1-binding protein.
    
 
 0.864
LOC110473388
Nodal.
      
 0.800
HIF1AN
Hypoxia-inducible factor 1-alpha inhibitor.
    
 
 0.767
MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1.
    
 
 0.757
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.