STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNKSPoly [ADP-ribose] polymerase. (1266 aa)    
Predicted Functional Partners:
RNF146
E3 ubiquitin-protein ligase RNF146.
    
 0.943
AXIN1
Axin-1.
    
 0.901
AXIN2
Axin-2.
    
 0.880
SH3BP2
SH3 domain-binding protein 2.
    
 
 0.725
GMDS
GDP-mannose 4,6 dehydratase.
    
 
 0.725
TNKS1BP1
Tankyrase-1-binding protein.
    
 
 0.706
MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1.
    
 
 0.692
HIF1AN
Hypoxia-inducible factor 1-alpha inhibitor.
    
 
 0.645
BABAM1
BRISC and BRCA1-A complex member 1.
    
 0.631
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
   
 0.599
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.