| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALDH18A1 | ASS1 | ENSLSDP00000020163 | ENSLSDP00000004246 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Argininosuccinate synthase. | 0.885 |
| ALDH18A1 | DHODH | ENSLSDP00000020163 | ENSLSDP00000000468 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.513 |
| ALDH18A1 | DPYD | ENSLSDP00000020163 | ENSLSDP00000015086 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | 0.765 |
| ALDH18A1 | GART | ENSLSDP00000020163 | ENSLSDP00000021446 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Trifunctional purine biosynthetic protein adenosine-3. | 0.795 |
| ALDH18A1 | LOC110479231 | ENSLSDP00000020163 | ENSLSDP00000021458 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Trifunctional purine biosynthetic protein adenosine-3. | 0.795 |
| ALDH18A1 | OTC | ENSLSDP00000020163 | ENSLSDP00000009268 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Ornithine carbamoyltransferase, mitochondrial; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.703 |
| ALDH18A1 | PPAT | ENSLSDP00000020163 | ENSLSDP00000011203 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.420 |
| ALDH18A1 | TMEM116 | ENSLSDP00000020163 | ENSLSDP00000006514 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Transmembrane protein 116. | 0.725 |
| ALDH18A1 | UMPS | ENSLSDP00000020163 | ENSLSDP00000002123 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Uridine 5'-monophosphate synthase. | 0.590 |
| ASS1 | ALDH18A1 | ENSLSDP00000004246 | ENSLSDP00000020163 | Argininosuccinate synthase. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.885 |
| ASS1 | GART | ENSLSDP00000004246 | ENSLSDP00000021446 | Argininosuccinate synthase. | Trifunctional purine biosynthetic protein adenosine-3. | 0.505 |
| ASS1 | LOC110479231 | ENSLSDP00000004246 | ENSLSDP00000021458 | Argininosuccinate synthase. | Trifunctional purine biosynthetic protein adenosine-3. | 0.505 |
| ASS1 | OTC | ENSLSDP00000004246 | ENSLSDP00000009268 | Argininosuccinate synthase. | Ornithine carbamoyltransferase, mitochondrial; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.999 |
| ASS1 | TMEM116 | ENSLSDP00000004246 | ENSLSDP00000006514 | Argininosuccinate synthase. | Transmembrane protein 116. | 0.835 |
| CEP68 | TMEM116 | ENSLSDP00000023555 | ENSLSDP00000006514 | Centrosomal protein. | Transmembrane protein 116. | 0.690 |
| DHODH | ALDH18A1 | ENSLSDP00000000468 | ENSLSDP00000020163 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.513 |
| DHODH | DPYD | ENSLSDP00000000468 | ENSLSDP00000015086 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | 0.455 |
| DHODH | GART | ENSLSDP00000000468 | ENSLSDP00000021446 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Trifunctional purine biosynthetic protein adenosine-3. | 0.681 |
| DHODH | LOC110479231 | ENSLSDP00000000468 | ENSLSDP00000021458 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Trifunctional purine biosynthetic protein adenosine-3. | 0.681 |
| DHODH | PPAT | ENSLSDP00000000468 | ENSLSDP00000011203 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.434 |