Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPINK2Serine protease inhibitor Kazal-type 2. (56 aa)    
Predicted Functional Partners:
LOC110470833
Pancreatic secretory trypsin inhibitor-like.
      
 0.682
PMPCA
Mitochondrial-processing peptidase subunit alpha.
    
   0.633
SPAM1
Hyaluronidase.
   
  
 0.602
WBP2NL
WW domain-binding protein 2.
      
 0.565
TECTB
Beta-tectorin.
      
 0.503
ENSLSDP00000004578
annotation not available
    
   0.481
NUDT8
Nucleoside diphosphate-linked moiety X motif 8, mitochondrial.
    
   0.481
RSPH1
Radial spoke head 1.
   
  
 0.456
MPPED1
Metallophosphoesterase domain-containing protein 1.
      
 0.454
MPPED2
Metallophosphoesterase MPPED2.
      
 0.454
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
Server load: low (28%) [HD]