STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC110469529Lethal(3)malignant brain tumor-like protein 3. (688 aa)    
Predicted Functional Partners:
RNF2
E3 ubiquitin-protein ligase RING2.
    
 0.625
TP53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
   
 0.616
ENSLSDP00000025365
annotation not available
      
 0.478
CBX8
Chromobox 8.
    
 0.474
YAF2
YY1-associated factor 2.
    
 0.461
RYBP
RING1 and YY1-binding protein.
    
 0.461
EED
Polycomb protein EED.
   
 0.455
RBPJ
Suppressor of hairless.
   
 
 0.443
CBX4
E3 SUMO-protein ligase CBX4.
    
 0.426
MPHOSPH8
M-phase phosphoprotein 8.
    
 0.421
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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