Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTPRUReceptor-type tyrosine-protein phosphatase U. (1450 aa)    
Predicted Functional Partners:
KIT
Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
  0.927
CTNNB1
Catenin beta-1.
    
 0.867
PTPRK
Receptor-type tyrosine-protein phosphatase kappa.
   
   0.850
PTPRE
Receptor-type tyrosine-protein phosphatase epsilon.
    
 
 0.761
CSF1R
Macrophage colony-stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
  0.731
PPM1M
Protein phosphatase 1M.
      
 0.706
ENPP5
Ectonucleotide pyrophosphatase/phosphodiesterase family member 5.
      
 0.682
DHX37
Putative ATP-dependent RNA helicase DHX37.
     
 0.582
PTS
6-pyruvoyltetrahydropterin synthase.
    
 
 0.580
JUP
Junction plakoglobin.
    
 0.542
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.