Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RLOC_00005885Transmembrane protease serine 11E. (286 aa)    
Predicted Functional Partners:
ENSLSDP00000026161
annotation not available
  
 
  0.598
KLK15
Kallikrein-15.
  
  
  0.584
TMPRSS4
Transmembrane protease serine 4; Belongs to the peptidase S1 family.
    
 
 0.519
TOP3B
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
      
 0.452
LOC110482935
BPTI/Kunitz domain-containing protein.
    
 0.428
RAB14
Ras-related protein Rab-14.
    
 0.426
CEP170
Centrosomal protein.
     
 0.425
CTRL
Chymotrypsin-like protease CTRL-1.
   
 0.424
SSC4D
Scavenger receptor cysteine-rich domain-containing group B protein.
 
  
  0.413
TMPRSS13
Transmembrane protease serine 13; Belongs to the peptidase S1 family.
      
 0.411
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
Server load: low (10%) [HD]