Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPOPSpeckle-type POZ protein. (374 aa)    
Predicted Functional Partners:
CUL3
Cullin-3; Belongs to the cullin family.
   
 0.994
GLI2
Zinc finger protein GLI2.
   
 0.989
GLI3
Transcriptional activator GLI3.
   
 0.986
GLI1
Zinc finger protein GLI1.
   
 0.977
SPOPL
Speckle-type POZ protein-like.
  
  
 
0.959
SUFU
Suppressor of fused.
     
 0.948
RBX1
E3 ubiquitin-protein ligase RBX1.
    
 0.895
CUL1
Cullin-1; Belongs to the cullin family.
   
 0.830
AR
Androgen receptor.
    
 
 0.786
DEK
Protein DEK.
    
 
 0.774
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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