Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa)    
Predicted Functional Partners:
TANK
TRAF family member-associated NF-kappa-B activator.
    
 0.999
MAVS
Mitochondrial antiviral-signaling protein.
    
 0.997
MAP3K14
Mitogen-activated protein kinase kinase kinase 14.
    
 0.997
TBK1
Serine/threonine-protein kinase TBK1.
   
 0.995
TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein.
    
 0.987
TLR4
Toll-like receptor 4; Belongs to the Toll-like receptor family.
   
 0.983
OTUB1
Ubiquitin thioesterase.
    
 0.958
MYD88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
    
 0.956
BIRC2
Inhibitor of apoptosis protein.
   
 0.955
TNFRSF13C
Uncharacterized protein.
    
 0.952
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
Server load: low (16%) [HD]