Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PGRMC1Membrane-associated progesterone receptor component 1; Belongs to the cytochrome b5 family. (192 aa)    
Predicted Functional Partners:
PGRMC2
Membrane-associated progesterone receptor component 2; Belongs to the cytochrome b5 family.
  
0.919
TMEM97
Sigma intracellular receptor 2.
     
 0.909
FECH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
    
 
 0.884
SERBP1
Plasminogen activator inhibitor 1 RNA-binding protein.
      
 0.873
CYP51A1
Lanosterol 14-alpha demethylase; Belongs to the cytochrome P450 family.
    
 
 0.848
SPCS2
Signal peptidase complex subunit 2.
    
   0.732
RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]
   
 
 0.725
PGR
Progesterone receptor.
      
 0.719
LOC110479740
Cytochrome P450 1A4; Belongs to the cytochrome P450 family.
    
   0.718
LOC110479741
Cytochrome P450 1A5.
    
   0.718
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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