Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HELLSLymphoid-specific helicase. (858 aa)    
Predicted Functional Partners:
WDR76
WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family.
   
 0.938
LOC110472216
POU domain protein.
    
 
 0.835
POLE3
DNA polymerase epsilon subunit 3.
    
 0.758
HESX1
Homeobox protein ANF-1.
    
 
 0.747
TTK
Dual specificity protein kinase TTK.
   
 
 0.733
RAD52
DNA repair protein RAD52.
    
 
 0.726
MYSM1
Histone H2A deubiquitinase MYSM1.
   
 0.702
CDC6
Cell division control protein 6.
   
 
 0.694
NATD1
Protein NATD1.
    
 0.691
MCM3
DNA helicase; Belongs to the MCM family.
   
 
 0.690
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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