HELLS protein (Lonchura striata) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

HELLS

Lymphoid-specific helicase. (858 aa)

Predicted Functional Partners:

WDR76

0.788

POLE3

0.745

EXO1

0.736

CDC6

0.725

BPTF

0.720

FANCM

0.670

LOC110477051

0.670

BAZ1A

0.663

UHRF1

0.663

BAZ1B

0.663

Your Current Organism:

Lonchura striata

NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAZ1A	HELLS	ENSLSDP00000003076	ENSLSDP00000006802	Bromodomain adjacent to zinc finger domain protein 1A.	Lymphoid-specific helicase.	0.663
BAZ1A	POLE3	ENSLSDP00000003076	ENSLSDP00000021090	Bromodomain adjacent to zinc finger domain protein 1A.	DNA polymerase epsilon subunit 3.	0.953
BAZ1B	BPTF	ENSLSDP00000013679	ENSLSDP00000021717	Tyrosine-protein kinase BAZ1B.	Nucleosome-remodeling factor subunit BPTF.	0.530
BAZ1B	HELLS	ENSLSDP00000013679	ENSLSDP00000006802	Tyrosine-protein kinase BAZ1B.	Lymphoid-specific helicase.	0.663
BAZ1B	POLE3	ENSLSDP00000013679	ENSLSDP00000021090	Tyrosine-protein kinase BAZ1B.	DNA polymerase epsilon subunit 3.	0.668
BPTF	BAZ1B	ENSLSDP00000021717	ENSLSDP00000013679	Nucleosome-remodeling factor subunit BPTF.	Tyrosine-protein kinase BAZ1B.	0.530
BPTF	HELLS	ENSLSDP00000021717	ENSLSDP00000006802	Nucleosome-remodeling factor subunit BPTF.	Lymphoid-specific helicase.	0.720
CDC6	EXO1	ENSLSDP00000010117	ENSLSDP00000019858	Cell division control protein 6.	Exonuclease 1.	0.955
CDC6	HELLS	ENSLSDP00000010117	ENSLSDP00000006802	Cell division control protein 6.	Lymphoid-specific helicase.	0.725
CDC6	POLE3	ENSLSDP00000010117	ENSLSDP00000021090	Cell division control protein 6.	DNA polymerase epsilon subunit 3.	0.680
EXO1	CDC6	ENSLSDP00000019858	ENSLSDP00000010117	Exonuclease 1.	Cell division control protein 6.	0.955
EXO1	FANCM	ENSLSDP00000019858	ENSLSDP00000010918	Exonuclease 1.	Fanconi anemia group M protein.	0.885
EXO1	HELLS	ENSLSDP00000019858	ENSLSDP00000006802	Exonuclease 1.	Lymphoid-specific helicase.	0.736
EXO1	LOC110477051	ENSLSDP00000019858	ENSLSDP00000020233	Exonuclease 1.	Fanconi anemia group M protein.	0.862
EXO1	POLE3	ENSLSDP00000019858	ENSLSDP00000021090	Exonuclease 1.	DNA polymerase epsilon subunit 3.	0.538
EXO1	WDR76	ENSLSDP00000019858	ENSLSDP00000011696	Exonuclease 1.	WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family.	0.574
FANCM	EXO1	ENSLSDP00000010918	ENSLSDP00000019858	Fanconi anemia group M protein.	Exonuclease 1.	0.885
FANCM	HELLS	ENSLSDP00000010918	ENSLSDP00000006802	Fanconi anemia group M protein.	Lymphoid-specific helicase.	0.670
FANCM	LOC110477051	ENSLSDP00000010918	ENSLSDP00000020233	Fanconi anemia group M protein.	Fanconi anemia group M protein.	0.994
FANCM	POLE3	ENSLSDP00000010918	ENSLSDP00000021090	Fanconi anemia group M protein.	DNA polymerase epsilon subunit 3.	0.431