Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GPC3Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (578 aa)    
Predicted Functional Partners:
NOTUM
Protein notum.
    
 0.728
SDC2
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
   
 0.722
SDC1
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
    
 0.643
SDC3
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
   
 
 0.638
DHH
Desert hedgehog protein.
    
 0.623
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.623
IHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.623
GPC6
Glypican-6; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
    
 0.573
GPC4
Glypican-4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
    
 0.573
GPC1
Glypican-1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
    
 0.573
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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