STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPYPancreatic hormone; Belongs to the NPY family. (58 aa)    
Predicted Functional Partners:
CEL
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
   
  0.829
SST
Somatostatin.
     
 0.702
PYY
Uncharacterized protein.
   
 
 0.645
CPA1
Carboxypeptidase A1.
   
  
 0.610
INS
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
  
 0.586
NPY2R
Neuropeptide Y receptor type 2; Belongs to the G-protein coupled receptor 1 family.
   
 0.583
LOC110482733
Neuropeptide Y receptor type 2; Belongs to the G-protein coupled receptor 1 family.
   
 0.583
RIMS2
Regulating synaptic membrane exocytosis protein 2.
   
 
 0.577
LOC110479562
Somatotropin.
   
    0.570
LOC110471658
Growth hormone.
   
    0.570
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.