Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TWNKTwinkle protein, mitochondrial. (668 aa)    
Predicted Functional Partners:
POLG
DNA polymerase subunit gamma-1.
   
 
 0.951
POLG2
DNA polymerase subunit gamma-2, mitochondrial.
     
 0.923
POLRMT
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family.
   
 
 0.886
SSBP1
Single-stranded DNA-binding protein, mitochondrial.
   
 
 0.873
CPOX
Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial.
    
   0.850
TFAM
Transcription factor A, mitochondrial.
     
 0.796
PTGES2
Prostaglandin E synthase 2.
    
   0.761
ENSLSDP00000002936
annotation not available
    
 
 0.749
NUBPL
Iron-sulfur protein NUBPL.
    
 
 0.749
RMND1
Required for meiotic nuclear division protein 1.
      
 0.745
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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