Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LZTS2Leucine zipper putative tumor suppressor 2. (617 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta-1.
   
 0.924
LZTS1
Leucine zipper putative tumor suppressor 1.
    
   0.854
SIPA1L1
Signal-induced proliferation-associated 1-like protein 1.
    
 
 0.773
DYRK1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A.
    
 
 0.724
SIPA1L2
Signal-induced proliferation-associated 1-like protein 2.
    
 
 0.688
AFDN
Afadin.
    
 
 0.684
UNC79
Protein unc-79.
    
 0.634
DLG5
Disks large 5; Belongs to the MAGUK family.
    
 
 0.573
TMEM86A
Lysoplasmalogenase-like protein TMEM86A.
      
 0.566
KATNB1
Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
      
 0.566
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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