Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DEF8Differentially expressed in FDCP 8. (440 aa)    
Predicted Functional Partners:
TCF25
Transcription factor 25.
      
 0.836
SAMSN1
SAM domain-containing protein SAMSN-1.
   
  
 0.689
ABI3
ABI gene family member 3.
      
 0.682
MTHFSD
Methenyltetrahydrofolate synthase domain-containing protein.
      
 0.678
PDCD5
Programmed cell death protein 5.
      
 0.667
ZNF276
Zinc finger protein 276.
      
 0.656
RRBP1
Ribosome-binding protein 1.
      
 0.601
MC1R
Melanocortin 1 receptor.
      
 0.594
MC5R
Melanocortin receptor 5.
      
 0.590
ENSLSDP00000023972
annotation not available
   
  
 0.577
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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