Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
HDAC5Histone deacetylase 5. (1604 aa)    
Predicted Functional Partners:
ARID4A
AT-rich interactive domain-containing protein 4A.
    
 0.728
ARID4B
AT-rich interactive domain-containing protein 4B.
    
 0.728
WDR90
WD repeat-containing protein 90.
    
 0.713
LOC110478774
E3 SUMO-protein ligase RanBP2.
   
 0.685
NME8
Thioredoxin domain-containing protein 3; Belongs to the NDK family.
   
 
 0.676
VCP
Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family.
   
 0.672
MEF2D
Myocyte-specific enhancer factor 2D.
   
 
 0.671
UBE2I
SUMO-conjugating enzyme UBC9; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.657
SIRT1
NAD-dependent protein deacetylase sirtuin-1.
    
 0.616
EP300
Histone acetyltransferase p300.
    
 0.611
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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