| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| COQ6 | LCMT1 | ENSLSDP00000003357 | ENSLSDP00000009823 | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. | 0.507 |
| COQ6 | PUM1 | ENSLSDP00000003357 | ENSLSDP00000009809 | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | Pumilio 1. | 0.694 |
| COQ6 | PUM2 | ENSLSDP00000003357 | ENSLSDP00000020992 | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | Pumilio 2. | 0.694 |
| COQ6 | RSRC2 | ENSLSDP00000003357 | ENSLSDP00000006380 | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | Arginine/serine-rich coiled-coil protein 2. | 0.505 |
| COQ6 | SLC25A32 | ENSLSDP00000003357 | ENSLSDP00000007367 | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | Mitochondrial folate transporter/carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.829 |
| FLAD1 | SLC25A32 | ENSLSDP00000000512 | ENSLSDP00000007367 | FAD synthase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily. | Mitochondrial folate transporter/carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.621 |
| GLDC | SLC25A32 | ENSLSDP00000018945 | ENSLSDP00000007367 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | Mitochondrial folate transporter/carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.872 |
| LCMT1 | COQ6 | ENSLSDP00000009823 | ENSLSDP00000003357 | Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | 0.507 |
| LCMT1 | SLC25A32 | ENSLSDP00000009823 | ENSLSDP00000007367 | Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. | Mitochondrial folate transporter/carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.735 |
| PCMTD1 | SLC25A32 | ENSLSDP00000020375 | ENSLSDP00000007367 | Protein-L-isoaspartate O-methyltransferase domain-containing protein 1. | Mitochondrial folate transporter/carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.680 |
| PUM1 | COQ6 | ENSLSDP00000009809 | ENSLSDP00000003357 | Pumilio 1. | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | 0.694 |
| PUM1 | SLC25A32 | ENSLSDP00000009809 | ENSLSDP00000007367 | Pumilio 1. | Mitochondrial folate transporter/carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.635 |
| PUM2 | COQ6 | ENSLSDP00000020992 | ENSLSDP00000003357 | Pumilio 2. | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | 0.694 |
| PUM2 | SLC25A32 | ENSLSDP00000020992 | ENSLSDP00000007367 | Pumilio 2. | Mitochondrial folate transporter/carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.635 |
| RGS3 | RIMS2 | ENSLSDP00000021086 | ENSLSDP00000007268 | Regulator of G-protein signaling 3. | Regulating synaptic membrane exocytosis protein 2. | 0.479 |
| RGS3 | SLC25A32 | ENSLSDP00000021086 | ENSLSDP00000007367 | Regulator of G-protein signaling 3. | Mitochondrial folate transporter/carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.592 |
| RIMS2 | RGS3 | ENSLSDP00000007268 | ENSLSDP00000021086 | Regulating synaptic membrane exocytosis protein 2. | Regulator of G-protein signaling 3. | 0.479 |
| RIMS2 | SLC25A32 | ENSLSDP00000007268 | ENSLSDP00000007367 | Regulating synaptic membrane exocytosis protein 2. | Mitochondrial folate transporter/carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.590 |
| RSRC2 | COQ6 | ENSLSDP00000006380 | ENSLSDP00000003357 | Arginine/serine-rich coiled-coil protein 2. | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | 0.505 |
| RSRC2 | SLC25A32 | ENSLSDP00000006380 | ENSLSDP00000007367 | Arginine/serine-rich coiled-coil protein 2. | Mitochondrial folate transporter/carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.833 |