| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AACS | ACAT1 | ENSLSDP00000007631 | ENSLSDP00000024885 | Acetoacetyl-CoA synthetase. | Acetyl-CoA acetyltransferase A, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family. | 0.963 |
| AACS | ACAT2 | ENSLSDP00000007631 | ENSLSDP00000021479 | Acetoacetyl-CoA synthetase. | Acetyl-CoA acetyltransferase, cytosolic; Belongs to the thiolase-like superfamily. Thiolase family. | 0.951 |
| AACS | BDH2 | ENSLSDP00000007631 | ENSLSDP00000010973 | Acetoacetyl-CoA synthetase. | 3-hydroxybutyrate dehydrogenase type 2. | 0.928 |
| AACS | EHHADH | ENSLSDP00000007631 | ENSLSDP00000017245 | Acetoacetyl-CoA synthetase. | Peroxisomal bifunctional enzyme; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.941 |
| AACS | HADH | ENSLSDP00000007631 | ENSLSDP00000017687 | Acetoacetyl-CoA synthetase. | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial. | 0.953 |
| AACS | HMGCL | ENSLSDP00000007631 | ENSLSDP00000021601 | Acetoacetyl-CoA synthetase. | Hydroxymethylglutaryl-CoA lyase, mitochondrial. | 0.945 |
| AACS | HMGCLL1 | ENSLSDP00000007631 | ENSLSDP00000000169 | Acetoacetyl-CoA synthetase. | 3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic. | 0.945 |
| AACS | HMGCS1 | ENSLSDP00000007631 | ENSLSDP00000007733 | Acetoacetyl-CoA synthetase. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.943 |
| AACS | HMGCS2 | ENSLSDP00000007631 | ENSLSDP00000012919 | Acetoacetyl-CoA synthetase. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.930 |
| AACS | OXCT1 | ENSLSDP00000007631 | ENSLSDP00000012710 | Acetoacetyl-CoA synthetase. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.926 |
| ACAT1 | AACS | ENSLSDP00000024885 | ENSLSDP00000007631 | Acetyl-CoA acetyltransferase A, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family. | Acetoacetyl-CoA synthetase. | 0.963 |
| ACAT1 | ACAT2 | ENSLSDP00000024885 | ENSLSDP00000021479 | Acetyl-CoA acetyltransferase A, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyl-CoA acetyltransferase, cytosolic; Belongs to the thiolase-like superfamily. Thiolase family. | 0.913 |
| ACAT1 | EHHADH | ENSLSDP00000024885 | ENSLSDP00000017245 | Acetyl-CoA acetyltransferase A, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family. | Peroxisomal bifunctional enzyme; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.970 |
| ACAT1 | HADH | ENSLSDP00000024885 | ENSLSDP00000017687 | Acetyl-CoA acetyltransferase A, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family. | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial. | 0.987 |
| ACAT1 | HMGCL | ENSLSDP00000024885 | ENSLSDP00000021601 | Acetyl-CoA acetyltransferase A, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family. | Hydroxymethylglutaryl-CoA lyase, mitochondrial. | 0.948 |
| ACAT1 | HMGCLL1 | ENSLSDP00000024885 | ENSLSDP00000000169 | Acetyl-CoA acetyltransferase A, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic. | 0.948 |
| ACAT1 | HMGCS1 | ENSLSDP00000024885 | ENSLSDP00000007733 | Acetyl-CoA acetyltransferase A, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.989 |
| ACAT1 | HMGCS2 | ENSLSDP00000024885 | ENSLSDP00000012919 | Acetyl-CoA acetyltransferase A, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.990 |
| ACAT1 | OXCT1 | ENSLSDP00000024885 | ENSLSDP00000012710 | Acetyl-CoA acetyltransferase A, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.971 |
| ACAT2 | AACS | ENSLSDP00000021479 | ENSLSDP00000007631 | Acetyl-CoA acetyltransferase, cytosolic; Belongs to the thiolase-like superfamily. Thiolase family. | Acetoacetyl-CoA synthetase. | 0.951 |