Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PIEZO1Piezo-type mechanosensitive ion channel component. (576 aa)    
Predicted Functional Partners:
ENSLSDP00000007623
annotation not available
 
     0.943
WDHD1
WD repeat and HMG-box DNA-binding protein 1.
   
 
 0.804
MCM4
DNA helicase; Belongs to the MCM family.
   
 0.774
CDC45
Cell division control protein 45.
   
 0.761
TIPIN
TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.
   
 
 0.753
TP53BP1
Tumor suppressor p53-binding protein 1.
   
 
 0.734
ATR
Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family.
   
 
 0.734
CHEK2
Serine/threonine-protein kinase Chk2.
    
 
 0.729
CDC6
Cell division control protein 6.
   
 0.706
RAD17
Cell cycle checkpoint protein RAD17.
   
 
 0.696
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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