Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACTN1-2Alpha-actinin-1. (247 aa)    
Predicted Functional Partners:
VCL
Vinculin.
   
 
 0.851
TNNI2
Troponin I, fast skeletal muscle.
   
 0.704
MYOZ2
Myozenin-2.
   
 
 0.701
PDLIM1
PDZ and LIM domain protein 3.
   
 
 0.697
TNNC2
Troponin C, skeletal muscle.
   
 0.643
CAMK2B
Calcium/calmodulin-dependent protein kinase type II subunit beta.
   
 0.626
CAMK2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha; Belongs to the protein kinase superfamily.
   
 0.626
CAMK2D
Calcium/calmodulin-dependent protein kinase type II subunit delta.
   
 0.626
ACTN2
Alpha-actinin-2.
   
 0.614
PARVB
Beta-parvin.
     
 0.607
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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