Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RNF166E3 ubiquitin-protein ligase RNF166. (241 aa)    
Predicted Functional Partners:
PARP11
Poly [ADP-ribose] polymerase.
    
  0.856
RNF114
E3 ubiquitin-protein ligase RNF114.
    
   0.837
ZC3HC1
NIPA-like protein.
      
 0.705
KLHL28
Kelch-like protein 28.
    
 
 0.705
DTX3L
E3 ubiquitin-protein ligase DTX3L.
   
 
 0.677
ZBTB39
Zinc finger and BTB domain-containing protein 39.
   
 0.674
ZFP91
E3 ubiquitin-protein ligase ZFP91.
   
 0.594
CARM1
Histone-arginine methyltransferase CARM1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
    
 
 0.593
LOC110480927
Zinc finger protein 827.
   
 0.592
NAE1
NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
     
 0.584
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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