Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TLE1Transducin-like enhancer protein 1. (772 aa)    
Predicted Functional Partners:
LEF1
Lymphoid enhancer-binding factor 1.
    
 0.957
TCF7L2
Transcription factor 7-like 2.
    
 0.951
LEF1_0
Lymphoid enhancer-binding factor 1.
    
 0.949
RBPJ
Suppressor of hairless.
    
 0.917
RBPJL
Recombining binding protein suppressor of hairless-like protein.
    
 0.916
HDAC2
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
    
 0.907
XIAP
E3 ubiquitin-protein ligase XIAP.
    
  0.652
TBX20
T-box transcription factor TBX20.
    
 
 0.590
HDAC8
Histone deacetylase 8.
    
 0.555
HDAC1
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
    
 0.555
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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