Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
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Experiments
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[Homology]
Score
KAT6BHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1731 aa)    
Predicted Functional Partners:
MEAF6
Chromatin modification-related protein MEAF6.
   
 0.938
BRPF1
Peregrin.
   
 0.900
BRD1
Bromodomain-containing protein 1.
   
 0.881
TRRAP
Transformation/transcription domain-associated protein; Belongs to the PI3/PI4-kinase family.
   
 0.833
MSL2
E3 ubiquitin-protein ligase MSL2.
   
 0.828
TP53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.826
KANSL3
KAT8 regulatory NSL complex subunit 3.
    
 0.824
MSL1
Male-specific lethal 1.
    
 0.824
ING5
Inhibitor of growth protein.
    
 0.823
ING4
Inhibitor of growth protein.
    
 0.823
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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