Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DHX8ATP-dependent RNA helicase DHX8. (1192 aa)    
Predicted Functional Partners:
CDC40
Pre-mRNA-processing factor 17.
   
 0.985
SYF2
Pre-mRNA-splicing factor SYF2.
    
 0.980
CACTIN
Cactin.
    
 0.979
NKAP
NF-kappa-B-activating protein.
   
 0.977
CCDC12
Coiled-coil domain-containing protein 12.
    
  0.974
CWC22
Pre-mRNA-splicing factor CWC22.
   
 0.970
PPIL1
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 0.967
CRNKL1
Crooked neck-like protein 1.
   
 0.959
CHERP
Calcium homeostasis endoplasmic reticulum protein.
   
 0.955
PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3.
   
 0.952
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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