SCTR protein (Lonchura striata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SCTR

Secretin receptor. (449 aa)

Predicted Functional Partners:

VIP

0.796

ADCYAP1

0.734

GHRH

0.652

CFTR

0.609

PTH

0.596

PTHLH

0.588

SCT

0.581

GPR22

0.548

GNB1

0.537

GNB4

0.537

Your Current Organism:

Lonchura striata

NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCYAP1	GHRH	ENSLSDP00000005304	ENSLSDP00000019754	Glucagon family neuropeptide.	VIP peptide.	0.600
ADCYAP1	GNB1	ENSLSDP00000005304	ENSLSDP00000007676	Glucagon family neuropeptide.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	0.634
ADCYAP1	GNB4	ENSLSDP00000005304	ENSLSDP00000007849	Glucagon family neuropeptide.	G protein subunit beta 4.	0.634
ADCYAP1	SCT	ENSLSDP00000005304	ENSLSDP00000005603	Glucagon family neuropeptide.	Secretin.	0.729
ADCYAP1	SCTR	ENSLSDP00000005304	ENSLSDP00000008288	Glucagon family neuropeptide.	Secretin receptor.	0.734
CFTR	SCTR	ENSLSDP00000005651	ENSLSDP00000008288	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	Secretin receptor.	0.609
GHRH	ADCYAP1	ENSLSDP00000019754	ENSLSDP00000005304	VIP peptide.	Glucagon family neuropeptide.	0.600
GHRH	GNB1	ENSLSDP00000019754	ENSLSDP00000007676	VIP peptide.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	0.474
GHRH	GNB4	ENSLSDP00000019754	ENSLSDP00000007849	VIP peptide.	G protein subunit beta 4.	0.474
GHRH	PTH	ENSLSDP00000019754	ENSLSDP00000011973	VIP peptide.	Parathyroid hormone.	0.573
GHRH	SCTR	ENSLSDP00000019754	ENSLSDP00000008288	VIP peptide.	Secretin receptor.	0.652
GHRH	VIP	ENSLSDP00000019754	ENSLSDP00000020287	VIP peptide.	Vasoactive intestinal peptide.	0.714
GNB1	ADCYAP1	ENSLSDP00000007676	ENSLSDP00000005304	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	Glucagon family neuropeptide.	0.634
GNB1	GHRH	ENSLSDP00000007676	ENSLSDP00000019754	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	VIP peptide.	0.474
GNB1	PTH	ENSLSDP00000007676	ENSLSDP00000011973	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	Parathyroid hormone.	0.428
GNB1	SCTR	ENSLSDP00000007676	ENSLSDP00000008288	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	Secretin receptor.	0.537
GNB1	VIP	ENSLSDP00000007676	ENSLSDP00000020287	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	Vasoactive intestinal peptide.	0.436
GNB4	ADCYAP1	ENSLSDP00000007849	ENSLSDP00000005304	G protein subunit beta 4.	Glucagon family neuropeptide.	0.634
GNB4	GHRH	ENSLSDP00000007849	ENSLSDP00000019754	G protein subunit beta 4.	VIP peptide.	0.474
GNB4	PTH	ENSLSDP00000007849	ENSLSDP00000011973	G protein subunit beta 4.	Parathyroid hormone.	0.428