ISLR2 protein (Lonchura striata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ISLR2

Immunoglobulin superfamily containing leucine-rich repeat protein 2. (339 aa)

Predicted Functional Partners:

BRINP2

0.598

LOC110478439

0.588

SAE1

0.584

G3BP1

0.571

SAMHD1

0.567

CDH12

0.519

ENSLSDP00000007594

0.512

LRRC8B

0.500

STOM

0.464

LRRC40

0.447

Your Current Organism:

Lonchura striata

NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRINP2	CDH12	ENSLSDP00000015817	ENSLSDP00000002282	BMP/retinoic acid-inducible neural-specific protein 2.	Cadherin-12; Cadherins are calcium-dependent cell adhesion proteins.	0.487
BRINP2	ISLR2	ENSLSDP00000015817	ENSLSDP00000008367	BMP/retinoic acid-inducible neural-specific protein 2.	Immunoglobulin superfamily containing leucine-rich repeat protein 2.	0.598
CDH12	BRINP2	ENSLSDP00000002282	ENSLSDP00000015817	Cadherin-12; Cadherins are calcium-dependent cell adhesion proteins.	BMP/retinoic acid-inducible neural-specific protein 2.	0.487
CDH12	ISLR2	ENSLSDP00000002282	ENSLSDP00000008367	Cadherin-12; Cadherins are calcium-dependent cell adhesion proteins.	Immunoglobulin superfamily containing leucine-rich repeat protein 2.	0.519
CDH12	LOC110478439	ENSLSDP00000002282	ENSLSDP00000015055	Cadherin-12; Cadherins are calcium-dependent cell adhesion proteins.	BMP/retinoic acid-inducible neural-specific protein 3.	0.487
ENSLSDP00000007594	ISLR2	ENSLSDP00000007594	ENSLSDP00000008367	annotation not available	Immunoglobulin superfamily containing leucine-rich repeat protein 2.	0.512
ENSLSDP00000007594	LRRC40	ENSLSDP00000007594	ENSLSDP00000007613	annotation not available	Leucine-rich repeat-containing protein 40.	0.917
G3BP1	ISLR2	ENSLSDP00000013780	ENSLSDP00000008367	Ras GTPase-activating protein-binding protein 1.	Immunoglobulin superfamily containing leucine-rich repeat protein 2.	0.571
G3BP1	SAE1	ENSLSDP00000013780	ENSLSDP00000004816	Ras GTPase-activating protein-binding protein 1.	SUMO-activating enzyme subunit 1.	0.714
G3BP1	SAMHD1	ENSLSDP00000013780	ENSLSDP00000012071	Ras GTPase-activating protein-binding protein 1.	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1.	0.482
G3BP1	STOM	ENSLSDP00000013780	ENSLSDP00000005205	Ras GTPase-activating protein-binding protein 1.	Erythrocyte band 7 integral membrane protein.	0.411
ISLR2	BRINP2	ENSLSDP00000008367	ENSLSDP00000015817	Immunoglobulin superfamily containing leucine-rich repeat protein 2.	BMP/retinoic acid-inducible neural-specific protein 2.	0.598
ISLR2	CDH12	ENSLSDP00000008367	ENSLSDP00000002282	Immunoglobulin superfamily containing leucine-rich repeat protein 2.	Cadherin-12; Cadherins are calcium-dependent cell adhesion proteins.	0.519
ISLR2	ENSLSDP00000007594	ENSLSDP00000008367	ENSLSDP00000007594	Immunoglobulin superfamily containing leucine-rich repeat protein 2.	annotation not available	0.512
ISLR2	G3BP1	ENSLSDP00000008367	ENSLSDP00000013780	Immunoglobulin superfamily containing leucine-rich repeat protein 2.	Ras GTPase-activating protein-binding protein 1.	0.571
ISLR2	LOC110478439	ENSLSDP00000008367	ENSLSDP00000015055	Immunoglobulin superfamily containing leucine-rich repeat protein 2.	BMP/retinoic acid-inducible neural-specific protein 3.	0.588
ISLR2	LRRC40	ENSLSDP00000008367	ENSLSDP00000007613	Immunoglobulin superfamily containing leucine-rich repeat protein 2.	Leucine-rich repeat-containing protein 40.	0.447
ISLR2	LRRC8B	ENSLSDP00000008367	ENSLSDP00000015635	Immunoglobulin superfamily containing leucine-rich repeat protein 2.	Volume-regulated anion channel subunit LRRC8B.	0.500
ISLR2	SAE1	ENSLSDP00000008367	ENSLSDP00000004816	Immunoglobulin superfamily containing leucine-rich repeat protein 2.	SUMO-activating enzyme subunit 1.	0.584
ISLR2	SAMHD1	ENSLSDP00000008367	ENSLSDP00000012071	Immunoglobulin superfamily containing leucine-rich repeat protein 2.	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1.	0.567