STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NSD3Histone-lysine N-methyltransferase NSD3. (1436 aa)    
Predicted Functional Partners:
PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1.
    
 0.677
PLOD2
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2.
    
 0.677
CAMKMT
Calmodulin-lysine N-methyltransferase.
     
 0.663
ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2.
    
 0.649
RBBP5
Retinoblastoma-binding protein 5.
    
 0.649
EED
Polycomb protein EED.
   
 0.646
SETD3
Protein-histidine N-methyltransferase.
     
 0.619
SETD7
Histone-lysine N-methyltransferase SETD7; Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes.
   
 0.589
MRE11
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
 0.579
SUZ12
Polycomb protein SUZ12.
    
 0.561
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.