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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HGDHomogentisate 1,2-dioxygenase. (439 aa)    
Predicted Functional Partners:
HPD
4-hydroxyphenylpyruvate dioxygenase.
  
 0.998
GSTZ1
Maleylacetoacetate isomerase; Belongs to the GST superfamily.
 
 
 0.996
HPDL
4-hydroxyphenylpyruvate dioxygenase-like protein.
  
 0.924
HPS4
Hermansky-Pudlak syndrome 4.
  
 0.893
ENSLSDP00000017438
annotation not available
  
 0.893
FAH
Fumarylacetoacetase.
  
 
 0.879
F13B
Abnormal spindle-like microcephaly-associated.
   
  
 0.800
FAHD2
Fumarylacetoacetate hydrolase domain-containing protein 2.
  
 
 0.781
FAHD1
Acylpyruvase FAHD1, mitochondrial.
  
 
 0.781
TAT
Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.
   
  
 0.768
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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