Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SEMA3ESemaphorin-3E; Belongs to the semaphorin family. (775 aa)    
Predicted Functional Partners:
PLXND1
Plexin-D1.
    
 0.994
EFR3A
Protein EFR3 A.
      
 0.874
DOK4
Docking protein 4.
      
 0.874
PLXNA4
Plexin-A4.
    
 0.794
PLXNC1
Plexin-C1.
    
 0.773
MFN2
Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
      
 0.709
PLXNA2
Plexin-A2.
    
 0.686
PLXNA1
Plexin-A1.
    
 0.686
VDAC1
Voltage-dependent anion-selective channel protein 1.
      
 0.683
PLXNB1
Plexin-B1.
    
 0.678
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.