Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DHX57Putative ATP-dependent RNA helicase DHX57. (1357 aa)    
Predicted Functional Partners:
RPSA
40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Belongs to the universal ribosomal protein uS2 family.
   
 
 0.810
LARP7
La-related protein 7.
   
 
 0.760
ITSN2
Intersectin-2.
    
 0.754
MLST8
Target of rapamycin complex subunit lst8.
      
 0.728
ITSN1
Intersectin-1.
    
  0.648
STXBP4
Syntaxin-binding protein 4.
     
 0.639
CAPRIN2
Caprin-2.
   
 
 0.633
RPL3
60S ribosomal protein L3; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.623
C2orf49
Ashwin.
   
 0.613
PPP1R3A
Protein phosphatase 1 regulatory subunit 3A.
    
 
 0.592
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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