STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
POLE3DNA polymerase epsilon subunit 3. (143 aa)    
Predicted Functional Partners:
POLE2
DNA polymerase epsilon subunit 2.
    
 0.999
POLE
DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
   
 0.999
POLE4
DNA polymerase epsilon subunit 4.
    
 0.999
CHRAC1
Chromatin accessibility complex protein 1.
    
 0.986
BAZ1A
Bromodomain adjacent to zinc finger domain protein 1A.
    
 
 0.953
POLA1
DNA polymerase.
   
 0.949
WRN
Werner syndrome ATP-dependent helicase.
    
 0.943
REV3L
DNA polymerase zeta catalytic subunit.
   
 0.925
DR1
Protein Dr1.
   
 
0.924
LOC110480129
Putative global transcription activator SNF2L1.
    
 0.909
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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