STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
METHepatocyte growth factor receptor. (1407 aa)    
Predicted Functional Partners:
CBL
E3 ubiquitin-protein ligase CBL.
   
 0.999
CBLB
E3 ubiquitin-protein ligase CBL-B.
   
 0.999
HGF
Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.
    
 0.994
GAB1
GRB2-associated-binding protein 1.
    
 0.992
GRB2
Growth factor receptor-bound protein 2.
    
 0.978
CRK
Adapter molecule crk.
   
 0.958
PTPRJ
Receptor-type tyrosine-protein phosphatase eta.
    
 0.956
LRIG1
Leucine-rich repeats and immunoglobulin-like domains protein 1.
    
 0.954
CRKL
Crk-like protein.
   
 0.952
CTNNB1
Catenin beta-1.
    
 0.952
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.