STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PC110_g10222Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)    
Predicted Functional Partners:
PC110_g1503
Histone H2A; Belongs to the histone H2A family.
 
 0.915
PC110_g1504
Histone H2A; Belongs to the histone H2A family.
 
 0.913
PC110_g11347
Histone H3; Belongs to the histone H3 family.
 
 
 0.897
PC110_g5288
Histone H3; Belongs to the histone H3 family.
 
 
 0.897
PC110_g10223
Histone domain-containing protein.
 
 
 0.876
PC110_g5397
Uncharacterized protein.
    
 0.863
PC110_g5289
Histone H2B; Belongs to the histone H2B family.
 
 0.861
PC110_g1199
Histone H2B; Belongs to the histone H2B family.
 
 0.861
PC110_g864
Histone H2A; Belongs to the histone H2A family.
   
 0.847
PC110_g4545
Hat1_N domain-containing protein.
    
 0.840
Your Current Organism:
Phytophthora cactorum
NCBI taxonomy Id: 29920
Other names: P. cactorum, Phytophthora sp. 748, Phytophthora sp. 753, Phytophthora sp. 764A, Phytophthora sp. 798, Phytophthora sp. 813, Phytophthora sp. CSL 20316642
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.