STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PC110_g5071Uncharacterized protein. (476 aa)    
Predicted Functional Partners:
PC110_g18733
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]
    
 
 0.854
PC110_g13788
WLM domain-containing protein.
    
 
 0.719
PC110_g2891
VWFA domain-containing protein.
    
 0.698
PC110_g17067
SAP domain-containing protein.
     
 0.670
PC110_g9402
Fanconi anemia group M protein.
   
 
 0.654
PC110_g10743
ERCC4 domain-containing protein.
   
 
 0.608
PC110_g15159
ERCC4 domain-containing protein.
   
 
 0.579
PC110_g9573
ERCC4 domain-containing protein.
   
 
 0.579
PC110_g6763
Lactamase_B domain-containing protein.
     
 0.569
PC110_g17889
Serine/threonine-protein kinase; Belongs to the PI3/PI4-kinase family.
     
 0.554
Your Current Organism:
Phytophthora cactorum
NCBI taxonomy Id: 29920
Other names: P. cactorum, Phytophthora sp. 748, Phytophthora sp. 753, Phytophthora sp. 764A, Phytophthora sp. 798, Phytophthora sp. 813, Phytophthora sp. CSL 20316642
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