SHG95453.1 protein (Ferrimonas marina) - STRING interaction network

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Experiments

Co-purification, co-crystallization, Yeast2Hybrid, Genetic Interactions, etc ... as imported from primary sources.

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Cooccurrence

Gene families whose occurrence patterns across genomes show similarities.

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Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.

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Genes that are sometimes fused into single open reading frames.

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Automated, unsupervised textmining - searching for proteins that are frequently mentioned together.

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Coexpression

Proteins whose genes are observed to be correlated in expression, across a large number of experiments.

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Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

SHG95453.1

Hypothetical protein. (61 aa)

Predicted Functional Partners:

SHG95386.1

Hypothetical protein.

0.450

SHG95421.1

Superoxide reductase.

0.450

Your Current Organism:

Ferrimonas marina

NCBI taxonomy Id: 299255
Other names: DSM 16917, F. marina, Ferrimonas marina Katsuta et al. 2005, MBIC 06480, NBRC 102583, strain A4D-4

Basic Settings

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meaning of network edges:

evidence

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( line thickness indicates the strength of data support )

active interaction sources:

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SHG95386.1	SHG95421.1	SAMN02745129_1247	SAMN02745129_1248	Hypothetical protein.	Superoxide reductase.	0.773
SHG95386.1	SHG95453.1	SAMN02745129_1247	SAMN02745129_1249	Hypothetical protein.	Hypothetical protein.	0.450
SHG95421.1	SHG95386.1	SAMN02745129_1248	SAMN02745129_1247	Superoxide reductase.	Hypothetical protein.	0.773
SHG95421.1	SHG95453.1	SAMN02745129_1248	SAMN02745129_1249	Superoxide reductase.	Hypothetical protein.	0.450
SHG95453.1	SHG95386.1	SAMN02745129_1249	SAMN02745129_1247	Hypothetical protein.	Hypothetical protein.	0.450
SHG95453.1	SHG95421.1	SAMN02745129_1249	SAMN02745129_1248	Hypothetical protein.	Superoxide reductase.	0.450

[ The below analysis is limited to the network nodes included in the specified statistical background ]

Network Stats

number of nodes:

number of edges:

average node degree:

3.27

avg. local clustering coefficient:

0.865

expected number of edges:

PPI enrichment p-value:

0.039

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:6216

Mixed, incl. Protein of unknown function DUF6624, and ATP-GRASP peptide maturase, grasp-with-spasm system

3 of 7

2.53

2.5

0.00014

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-168249

Innate Immune System

2 of 29

1.73

1.05

0.0173

MAP-168256

Immune System

2 of 38

1.62

1.01

0.0173

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR046732

Protein of unknown function DUF6624

2 of 3

2.72

1.13

0.0208

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