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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fbxl12F-box and leucine rich repeat protein 12. (386 aa)    
Predicted Functional Partners:
skp1
S-phase kinase associated protein 1.
   
 0.966
LOC114787973
Cullin-1.
    
 0.884
cul1
Cullin 1.
    
 0.884
LOC114793696
RING-box protein 1.
    
 0.804
LOC114793901
RING-box protein 1.
    
 0.804
CUL3
Cullin-3-like.
    
 0.748
LOC114787564
Cullin-3.
    
 0.748
LOC114786024
NEDD8.
    
 0.748
LOC114801645
Cullin-3-like.
    
 0.748
ENSDCDP00000031061
annotation not available
    
 0.748
Your Current Organism:
Denticeps clupeoides
NCBI taxonomy Id: 299321
Other names: D. clupeoides, denticle herring
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.